Zearalenone Induces Endoplasmic Reticulum Stress and Modulates the Expression of Phase I/II Enzymes in Human Liver Cells

Zearalenone (ZEN) is a mycotoxin produced by Fusarium species; however, its mechanisms of action in human livers have not been fully elucidated. Thus, we investigated the toxic mechanisms of ZEN in human liver cells. HepG2 cells were treated with ZEN (0–40 μg/mL) for up to 24 h. A significant decrea...

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Detalles Bibliográficos
Autores principales: Yoon, Jee Eun, Lee, Kwang Yong, Seok, Jin Sil, Cheng, Wei Nee, Kwon, Hyuk Cheol, Jeong, Chang Hee, Han, Sung Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020402/
https://www.ncbi.nlm.nih.gov/pubmed/31861425
http://dx.doi.org/10.3390/toxins12010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020402/
https://www.ncbi.nlm.nih.gov/pubmed/31861425
http://dx.doi.org/10.3390/toxins12010002

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