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Zearalenone Induces Endoplasmic Reticulum Stress and Modulates the Expression of Phase I/II Enzymes in Human Liver Cells
Zearalenone (ZEN) is a mycotoxin produced by Fusarium species; however, its mechanisms of action in human livers have not been fully elucidated. Thus, we investigated the toxic mechanisms of ZEN in human liver cells. HepG2 cells were treated with ZEN (0–40 μg/mL) for up to 24 h. A significant decrea...
Autores principales: | Yoon, Jee Eun, Lee, Kwang Yong, Seok, Jin Sil, Cheng, Wei Nee, Kwon, Hyuk Cheol, Jeong, Chang Hee, Han, Sung Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020402/ https://www.ncbi.nlm.nih.gov/pubmed/31861425 http://dx.doi.org/10.3390/toxins12010002 |
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