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An Inducible Cre-lox System to Analyze the Role of LLO in Listeria monocytogenes Pathogenesis

Listeriolysin O (LLO) is a pore-forming cytolysin that allows Listeria monocytogenes to escape from phagocytic vacuoles and enter the host cell cytosol. LLO is expressed continuously during infection, but it has been a challenge to evaluate the importance of LLO secreted in the host cell cytosol bec...

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Detalles Bibliográficos
Autores principales: Nguyen, Brittney N., Portnoy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020405/
https://www.ncbi.nlm.nih.gov/pubmed/31936068
http://dx.doi.org/10.3390/toxins12010038