Activation of the IRE1α Arm, but not the PERK Arm, of the Unfolded Protein Response Contributes to Fumonisin B1-Induced Hepatotoxicity

Previous studies by us or others have shown that endoplasmic reticulum (ER) stress was activated by fumonisin 1 (FB1) exposure, which is considered to be a critical event in the FB1-induced toxic effect. However, the detailed mechanisms underlying FB1-induced ER stress-mediated liver toxicity remain...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaoyi, Zhang, Enxiang, Yin, Shutao, Zhao, Chong, Fan, Lihong, Hu, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020448/
https://www.ncbi.nlm.nih.gov/pubmed/31963346
http://dx.doi.org/10.3390/toxins12010055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020448/
https://www.ncbi.nlm.nih.gov/pubmed/31963346
http://dx.doi.org/10.3390/toxins12010055

Ejemplares similares