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Activation of the IRE1α Arm, but not the PERK Arm, of the Unfolded Protein Response Contributes to Fumonisin B1-Induced Hepatotoxicity

Previous studies by us or others have shown that endoplasmic reticulum (ER) stress was activated by fumonisin 1 (FB1) exposure, which is considered to be a critical event in the FB1-induced toxic effect. However, the detailed mechanisms underlying FB1-induced ER stress-mediated liver toxicity remain...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaoyi, Zhang, Enxiang, Yin, Shutao, Zhao, Chong, Fan, Lihong, Hu, Hongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020448/ https://www.ncbi.nlm.nih.gov/pubmed/31963346 http://dx.doi.org/10.3390/toxins12010055

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