Predictability of drug-induced liver injury by machine learning

BACKGROUND: Drug-induced liver injury (DILI) is a major concern in drug development, as hepatotoxicity may not be apparent at early stages but can lead to life threatening consequences. The ability to predict DILI from in vitro data would be a crucial advantage. In 2018, the Critical Assessment Mass...

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Detalles Bibliográficos
Autores principales: Chierici, Marco, Francescatto, Margherita, Bussola, Nicole, Jurman, Giuseppe, Furlanello, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020573/
https://www.ncbi.nlm.nih.gov/pubmed/32054490
http://dx.doi.org/10.1186/s13062-020-0259-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020573/
https://www.ncbi.nlm.nih.gov/pubmed/32054490
http://dx.doi.org/10.1186/s13062-020-0259-4

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