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Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1

BACKGROUND: We used the Toponome Imaging System (TIS) to identify “patterns of marker expression”, referred to here as combinatorial molecular phenotypes (CMPs) in alveolar macrophages (AM) in response to the innate immune molecule, SP-A1. METHODS: We compared 114 AM from male SP-A deficient mice. O...

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Detalles Bibliográficos
Autores principales: Phelps, David S., Chinchilli, Vernon M., Weisz, Judith, Shearer, Debra, Zhang, Xuesheng, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020580/
https://www.ncbi.nlm.nih.gov/pubmed/32082572
http://dx.doi.org/10.1186/s40364-019-0181-z