Cargando…
Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1
BACKGROUND: We used the Toponome Imaging System (TIS) to identify “patterns of marker expression”, referred to here as combinatorial molecular phenotypes (CMPs) in alveolar macrophages (AM) in response to the innate immune molecule, SP-A1. METHODS: We compared 114 AM from male SP-A deficient mice. O...
Autores principales: | Phelps, David S., Chinchilli, Vernon M., Weisz, Judith, Shearer, Debra, Zhang, Xuesheng, Floros, Joanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020580/ https://www.ncbi.nlm.nih.gov/pubmed/32082572 http://dx.doi.org/10.1186/s40364-019-0181-z |
Ejemplares similares
-
Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice
por: Phelps, David S., et al.
Publicado: (2020) -
The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue
por: Phelps, David S., et al.
Publicado: (2022) -
Comparison of the Toponomes of Alveolar Macrophages From Wild Type and Surfactant Protein A Knockout Mice and Their Response to Infection
por: Phelps, David S., et al.
Publicado: (2022) -
Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A
por: Phelps, David S, et al.
Publicado: (2012) -
Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging
por: Tsotakos, Nikolaos, et al.
Publicado: (2016)