The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid

BACKGROUND: This study aimed to investigate the effects of RKI-1447, a selective inhibitor of Rho-associated ROCK kinases, in a mouse model of nonalcoholic fatty liver disease (NAFLD) induced by a high-fat diet, and in oleic acid-treated HepG2 human hepatocellular carcinoma cells in vitro. MATERIAL/...

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Detalles Bibliográficos
Autores principales: Wang, Jinshan, Jiang, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020744/
https://www.ncbi.nlm.nih.gov/pubmed/32026851
http://dx.doi.org/10.12659/MSM.919220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020744/
https://www.ncbi.nlm.nih.gov/pubmed/32026851
http://dx.doi.org/10.12659/MSM.919220

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