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The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid
BACKGROUND: This study aimed to investigate the effects of RKI-1447, a selective inhibitor of Rho-associated ROCK kinases, in a mouse model of nonalcoholic fatty liver disease (NAFLD) induced by a high-fat diet, and in oleic acid-treated HepG2 human hepatocellular carcinoma cells in vitro. MATERIAL/...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Scientific Literature, Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020744/ https://www.ncbi.nlm.nih.gov/pubmed/32026851 http://dx.doi.org/10.12659/MSM.919220 |