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Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation

BACKGROUND: Persistent myocardial ischemia post-myocardial infarction can lead to fatal ventricular arrhythmias such as ventricular tachycardia and fibrillation, both of which carry high mortality rates. Dexmedetomidine (Dex) is a highly selective α2-agonist used in surgery for congenital cardiac di...

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Detalles Bibliográficos
Autores principales: Wu, Shu-jie, Lin, Zhong-hao, Lin, Yuan-zheng, Rao, Zhi-heng, Lin, Jia-feng, Wu, Lian-pin, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020758/
https://www.ncbi.nlm.nih.gov/pubmed/32116751
http://dx.doi.org/10.3389/fphys.2020.00033