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Regenerative lineages and immune-mediated pruning in lung cancer metastasis

Developmental processes underlying normal tissue regeneration have been implicated in cancer, but the degree of their enactment during tumor progression and under the selective pressures of immune surveillance, remain unknown. Here, we show that human primary lung adenocarcinomas are characterized b...

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Detalles Bibliográficos
Autores principales: Laughney, Ashley M., Hu, Jing, Campbell, Nathaniel R., Bakhoum, Samuel F., Setty, Manu, Lavallée, Vincent-Philippe, Xie, Yubin, Masilionis, Ignas, Carr, Ambrose J., Kottapalli, Sanjay, Allaj, Viola, Mattar, Marissa, Rekhtman, Natasha, Xavier, Joao B., Mazutis, Linas, Poirier, John T., Rudin, Charles M., Pe’er, Dana, Massagué, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021003/
https://www.ncbi.nlm.nih.gov/pubmed/32042191
http://dx.doi.org/10.1038/s41591-019-0750-6