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A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

OBJECTIVES: We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. METHODS: We whole-genome sequenced 12 254 pneumococcal isolates from 29 countries on an Illumina HiSeq sequencer. Serotype, multilocus ST and antibiotic...

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Detalles Bibliográficos
Autores principales: Lo, Stephanie W, Gladstone, Rebecca A, van Tonder, Andries J, Du Plessis, Mignon, Cornick, Jennifer E, Hawkins, Paulina A, Madhi, Shabir A, Nzenze, Susan A, Kandasamy, Rama, Ravikumar, K L, Elmdaghri, Naima, Kwambana-Adams, Brenda, Almeida, Samanta Cristine Grassi, Skoczynska, Anna, Egorova, Ekaterina, Titov, Leonid, Saha, Samir K, Paragi, Metka, Everett, Dean B, Antonio, Martin, Klugman, Keith P, Li, Yuan, Metcalf, Benjamin J, Beall, Bernard, McGee, Lesley, Breiman, Robert F, Bentley, Stephen D, von Gottberg, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021099/
https://www.ncbi.nlm.nih.gov/pubmed/31789384
http://dx.doi.org/10.1093/jac/dkz477