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Synthesis of amino acids and peptides with bulky side chains via ligand-enabled carboxylate-directed γ-C(sp(3))–H arylation
Amino acids and peptides with bulky side chains are of significant importance in organic synthesis and modern medicinal chemistry. The efficient synthesis of these molecules with full enantiocontrol and high diversity remains challenging. Herein we report a Pd-catalyzed ligand-enabled γ-C(sp(3))–H a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021191/ https://www.ncbi.nlm.nih.gov/pubmed/32153751 http://dx.doi.org/10.1039/c9sc04482e |