A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes

The CRISPR/Cas system has significant potential to facilitate gene editing in a variety of bacterial species. CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) represent modifications of the CRISPR/Cas9 system utilizing a catalytically inactive Cas9 protein for transcription repression a...

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Detalles Bibliográficos
Autores principales: Spoto, Michelle, Guan, Changhui, Fleming, Elizabeth, Oh, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Resource Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021469/
https://www.ncbi.nlm.nih.gov/pubmed/32051236
http://dx.doi.org/10.1128/mSphere.00086-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021469/
https://www.ncbi.nlm.nih.gov/pubmed/32051236
http://dx.doi.org/10.1128/mSphere.00086-20

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