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A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes

The CRISPR/Cas system has significant potential to facilitate gene editing in a variety of bacterial species. CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) represent modifications of the CRISPR/Cas9 system utilizing a catalytically inactive Cas9 protein for transcription repression a...

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Detalles Bibliográficos
Autores principales:	Spoto, Michelle, Guan, Changhui, Fleming, Elizabeth, Oh, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Resource Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021469/ https://www.ncbi.nlm.nih.gov/pubmed/32051236 http://dx.doi.org/10.1128/mSphere.00086-20

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