Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

Structural characterization of the HIV-1 Envelope (Env) glycoprotein has facilitated the development of Env probes to isolate HIV-specific monoclonal antibodies (mAbs). However, preclinical studies have largely evaluated these virus-specific mAbs against chimeric viruses, which do not naturally infe...

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Detalles Bibliográficos
Autores principales: Pedreño-Lopez, Nuria, Dang, Christine M., Rosen, Brandon C., Ricciardi, Michael J., Bailey, Varian K., Gutman, Martin J., Gonzalez-Nieto, Lucas, Pauthner, Matthias G., Le, Khoa, Song, Ge, Andrabi, Raiees, Weisgrau, Kim L., Pomplun, Nicholas, Martinez-Navio, José M., Fuchs, Sebastian P., Wrammert, Jens, Rakasz, Eva G., Lifson, Jeffrey D., Martins, Mauricio A., Burton, Dennis R., Watkins, David I., Magnani, Diogo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021589/
https://www.ncbi.nlm.nih.gov/pubmed/32083148
http://dx.doi.org/10.1016/j.omtm.2020.01.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021589/
https://www.ncbi.nlm.nih.gov/pubmed/32083148
http://dx.doi.org/10.1016/j.omtm.2020.01.010

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