An isothermal shift assay for proteome scale drug-target identification

Most small molecule drugs act on living systems by physically interacting with specific proteins and modulating target function. Identification of drug binding targets, within the complex milieu of the human proteome, remains a challenging task of paramount importance in drug discovery. Existing app...

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Detalles Bibliográficos
Autores principales: Ball, Kerri A., Webb, Kristofor J., Coleman, Stephen J., Cozzolino, Kira A., Jacobsen, Jeremy, Jones, Kevin R., Stowell, Michael H. B., Old, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021718/
https://www.ncbi.nlm.nih.gov/pubmed/32060372
http://dx.doi.org/10.1038/s42003-020-0795-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021718/
https://www.ncbi.nlm.nih.gov/pubmed/32060372
http://dx.doi.org/10.1038/s42003-020-0795-6

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