Quantitative mechanisms of DNA damage sensing and signaling

DNA damage occurs abundantly during normal cellular proliferation. This necessitates that cellular DNA damage response and checkpoint pathways monitor the cellular DNA damage load and that DNA damage signaling is quantitative. Yet, how DNA lesions are counted and converted into a quantitative respon...

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Detalles Bibliográficos
Autores principales: Bantele, Susanne C. S., Pfander, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021746/
https://www.ncbi.nlm.nih.gov/pubmed/31227863
http://dx.doi.org/10.1007/s00294-019-01007-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021746/
https://www.ncbi.nlm.nih.gov/pubmed/31227863
http://dx.doi.org/10.1007/s00294-019-01007-4

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