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Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing

Mesenchymal stromal cells (MSC) have immunomodulatory effects impacting macrophages, promoting polarisation towards a reparative phenotype. CCL2 is a potent cytokine involved in the recruitment of macrophages. We hypothesised that MSC derived CCL2 may be involved in the MSC therapeutic effect by fac...

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Detalles Bibliográficos
Autores principales: Whelan, Derek S., Caplice, Noel M., Clover, Anthony J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021763/
https://www.ncbi.nlm.nih.gov/pubmed/32060374
http://dx.doi.org/10.1038/s41598-020-59174-1