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Extract from used Xpert MTB/RIF Ultra cartridges is useful for accurate second-line drug-resistant tuberculosis diagnosis with minimal rpoB-amplicon cross-contamination risk

Xpert MTB/RIF Ultra (Ultra) detects Mycobacterium tuberculosis and rifampicin resistance. Follow-on drug susceptibility testing (DST) requires additional sputum. Extract from the diamond-shaped chamber of the cartridge (dCE) of Ultra’s predecessor, Xpert MTB/RIF (Xpert), is useful for MTBDRsl-based...

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Detalles Bibliográficos
Autores principales: Venter, Rouxjeane, Minnies, Stephanie, Derendinger, Brigitta, Tshivhula, Happy, de Vos, Margaretha, Dolby, Tania, Ruiters, Ashley, Warren, Robin M., Theron, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021780/
https://www.ncbi.nlm.nih.gov/pubmed/32060311
http://dx.doi.org/10.1038/s41598-020-59164-3