Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study

Preclinical models of psychosis propose that hippocampal glutamatergic neuron hyperactivity drives increased striatal dopaminergic activity, which underlies the development of psychotic symptoms. The aim of this study was to examine the relationship between hippocampal glutamate and subcortical dopa...

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Detalles Bibliográficos
Autores principales: Howes, Oliver D., Bonoldi, Ilaria, McCutcheon, Robert A., Azis, Matilda, Antoniades, Mathilde, Bossong, Matthijs, Modinos, Gemma, Perez, Jesus, Stone, James M., Santangelo, Barbara, Veronese, Mattia, Grace, Anthony, Allen, Paul, McGuire, Philip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021794/
https://www.ncbi.nlm.nih.gov/pubmed/31618752
http://dx.doi.org/10.1038/s41386-019-0541-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021794/
https://www.ncbi.nlm.nih.gov/pubmed/31618752
http://dx.doi.org/10.1038/s41386-019-0541-2

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