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In vitro self-replication and multicistronic expression of large synthetic genomes

The generation of a chemical system capable of replication and evolution is a key objective of synthetic biology. This could be achieved by in vitro reconstitution of a minimal self-sustaining central dogma consisting of DNA replication, transcription and translation. Here, we present an in vitro tr...

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Detalles Bibliográficos
Autores principales: Libicher, K., Hornberger, R., Heymann, M., Mutschler, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021806/
https://www.ncbi.nlm.nih.gov/pubmed/32060271
http://dx.doi.org/10.1038/s41467-020-14694-2