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Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons

Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from the cutaneous secretions of the amphibian, Leptodactylus vastus, as a...

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Detalles Bibliográficos
Autores principales: Sousa, Nayara A., Oliveira, Guilherme A. L., de Oliveira, Ana Patrícia, Lopes, André Luís F., Iles, Bruno, Nogueira, Kerolayne M., Araújo, Thiago S. L., Souza, Luan K. M., Araújo, Alyne R., Ramos-Jesus, Joilson, Plácido, Alexandra, Amaral, Constança, Campelo, Yuri D. M., Barbosa, Eder Alves, Portugal, Camila C., Socodato, Renato, Lobo, Andrea, Relvas, Joao, Bemquerer, Marcelo, Eaton, Peter, Leite, José Roberto S. A., Medeiros, Jand Venes R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021831/
https://www.ncbi.nlm.nih.gov/pubmed/32060388
http://dx.doi.org/10.1038/s41598-020-59665-1