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Matrix protease production, epithelial-to-mesenchymal transition marker expression and invasion of glioblastoma cells in response to osmotic or hydrostatic pressure

Both hydrostatic and osmotic pressures are altered in the tumour microenvironment. Glioblastoma (GBM) is a brain tumour with high invasiveness and poor prognosis. We hypothesized that physical and osmotic forces regulate glioblastoma (GBM) invasiveness. The osmotic pressure of GBM cell culture mediu...

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Detalles Bibliográficos
Autores principales: Pu, Wenjun, Qiu, Jiawen, Riggins, Gregory J., Parat, Marie-Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021835/
https://www.ncbi.nlm.nih.gov/pubmed/32060379
http://dx.doi.org/10.1038/s41598-020-59462-w