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Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study

INTRODUCTION: The B cell survival factor B lymphocyte stimulator (BLyS) is elevated in patients with systemic lupus erythematosus (SLE) and associated with disease activity. Belimumab, a monoclonal antibody specific for soluble BLyS, is approved for the treatment of adults with active, autoantibody-...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wan, Weiguo, Miao, Liyan, Wu, Jian, Dong, Jun, Shen, Yinghua, Xiong, Cui, Li, Chao, Xue, Yu, Cao, Guoying, Ma, Peiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021845/
https://www.ncbi.nlm.nih.gov/pubmed/31953740
http://dx.doi.org/10.1007/s40744-020-00193-9