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N-terminal domain of the architectural protein CTCF has similar structural organization and ability to self-association in bilaterian organisms

CTCF is the main architectural protein found in most of the examined bilaterian organisms. The cluster of the C2H2 zinc-finger domains involved in recognition of long DNA-binding motif is only part of the protein that is evolutionarily conserved, while the N-terminal domain (NTD) has different seque...

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Detalles Bibliográficos
Autores principales: Bonchuk, Artem, Kamalyan, Sofia, Mariasina, Sofia, Boyko, Konstantin, Popov, Vladimir, Maksimenko, Oksana, Georgiev, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021899/
https://www.ncbi.nlm.nih.gov/pubmed/32060375
http://dx.doi.org/10.1038/s41598-020-59459-5