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Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy

Sphingosine 1-phosphate receptor-1 (S1PR1) is essential for embryonic vascular development and maturation. In the adult, it is a key regulator of vascular barrier function and inflammatory processes. Its roles in tumor angiogenesis, tumor growth, and metastasis are not well understood. In this paper...

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Detalles Bibliográficos
Autores principales: Cartier, Andreane, Leigh, Tani, Liu, Catherine H., Hla, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022165/
https://www.ncbi.nlm.nih.gov/pubmed/31988136
http://dx.doi.org/10.1073/pnas.1906246117