Optimization of a Plasmodium falciparum circumsporozoite protein repeat vaccine using the tobacco mosaic virus platform

Plasmodium falciparum vaccine RTS,S/AS01 is based on the major NPNA repeat and the C-terminal region of the circumsporozoite protein (CSP). RTS,S-induced NPNA-specific antibody titer and avidity have been associated with high-level protection in naïve subjects, but efficacy and longevity in target p...

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Detalles Bibliográficos
Autores principales: Langowski, Mark D., Khan, Farhat A., Bitzer, Alexis A., Genito, Christopher J., Schrader, Andrew J., Martin, Monica L., Soto, Kimberly, Zou, Xiaoyan, Hadiwidjojo, Sri, Beck, Zoltan, Matyas, Gary R., Livingstone, Merricka C., Batchelor, Adrian H., Dutta, Sheetij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022184/
https://www.ncbi.nlm.nih.gov/pubmed/31988134
http://dx.doi.org/10.1073/pnas.1911792117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022184/
https://www.ncbi.nlm.nih.gov/pubmed/31988134
http://dx.doi.org/10.1073/pnas.1911792117

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