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High-complexity extracellular barcoding using a viral hemagglutinin

While single-cell sequencing technologies have revealed tissue heterogeneity, resolving mixed cellular libraries into cellular clones is essential for many pooled screens and clonal lineage tracing. Fluorescent proteins are limited in number, while DNA barcodes can only be read after cell lysis. To...

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Detalles Bibliográficos
Autores principales: Mullokandov, Gavriel, Vijayakumar, Gayathri, Leon, Paul, Henry, Carole, Wilson, Patrick C., Krammer, Florian, Palese, Peter, Brown, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022207/
https://www.ncbi.nlm.nih.gov/pubmed/31988118
http://dx.doi.org/10.1073/pnas.1919182117