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Biochemical and Structural Characterization of OXA-405, an OXA-48 Variant with Extended-Spectrum β-Lactamase Activity

OXA-48-producing Enterobacterales have now widely disseminated globally. A sign of their extensive spread is the identification of an increasing number of OXA-48 variants. Among them, three are particularly interesting, OXA-163, OXA-247 and OXA-405, since they have lost carbapenem activities and gai...

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Detalles Bibliográficos
Autores principales: Oueslati, Saoussen, Retailleau, Pascal, Marchini, Ludovic, Dortet, Laurent, Bonnin, Rémy A., Iorga, Bogdan I., Naas, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022249/
https://www.ncbi.nlm.nih.gov/pubmed/31877796
http://dx.doi.org/10.3390/microorganisms8010024