Optimization of Rifapentine-Loaded Lipid Nanoparticles Using a Quality-by-Design Strategy

This work aims to optimize and assess the potential use of lipid nanoparticles, namely nanostructured lipid carriers (NLCs), as drug delivery systems of rifapentine (RPT) for the treatment of tuberculosis (TB). A Box–Behnken design was used to increase drug encapsulation efficiency (EE) and loading...

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Detalles Bibliográficos
Autores principales: Magalhães, Joana, L. Chaves, Luise, C. Vieira, Alexandre, G. Santos, Susana, Pinheiro, Marina, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022298/
https://www.ncbi.nlm.nih.gov/pubmed/31963468
http://dx.doi.org/10.3390/pharmaceutics12010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022298/
https://www.ncbi.nlm.nih.gov/pubmed/31963468
http://dx.doi.org/10.3390/pharmaceutics12010075

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