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Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway

The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N-terminal asparagine amidohydrolase 1 (NTAN1) int...

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Detalles Bibliográficos
Autores principales: Park, Joon Sung, Lee, Jae-Young, Nguyen, Yen Thi Kim, Kang, Nae-Won, Oh, Eun Kyung, Jang, Dong Man, Kim, Hyun-Jung, Kim, Dae-Duk, Han, Byung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022378/
https://www.ncbi.nlm.nih.gov/pubmed/31968674
http://dx.doi.org/10.3390/biom10010163