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Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity
Apolipoprotein E (ApoE) has become a primary focus of research after the discovery of its strong linkage to Alzheimer’s disease (AD), where the ApoE4 variant is the highest genetic risk factor for this disease. ApoE is commonly found in amyloid deposits of different origins, and its interaction with...
Autores principales: | Gharibyan, Anna L., Islam, Tohidul, Pettersson, Nina, Golchin, Solmaz A., Lundgren, Johanna, Johansson, Gabriella, Genot, Mélany, Schultz, Nina, Wennström, Malin, Olofsson, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022431/ https://www.ncbi.nlm.nih.gov/pubmed/31947546 http://dx.doi.org/10.3390/biom10010134 |
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