Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5

The voltage-gated potassium channel Kv1.5, which mediates the cardiac ultra-rapid delayed-rectifier (I(Kur)) current in human cells, has a crucial role in atrial fibrillation. Therefore, the design of selective Kv1.5 modulators is essential for the treatment of pathophysiological conditions involvin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Zefeng, Ruan, Songsong, Ma, Xiaoming, Feng, Qian, Xie, Zhuosong, Nie, Zhuang, Fan, Peinan, Qian, Mingcheng, He, Xirui, Wu, Shaoping, Zhang, Yongmin, Zheng, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022446/
https://www.ncbi.nlm.nih.gov/pubmed/31861703
http://dx.doi.org/10.3390/biom10010010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022446/
https://www.ncbi.nlm.nih.gov/pubmed/31861703
http://dx.doi.org/10.3390/biom10010010

Ejemplares similares