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Oral Treatment of Spontaneously Hypertensive Rats with Captopril-Surface Functionalized Furosemide-Loaded Multi-Wall Lipid-Core Nanocapsules

Multi-wall lipid-core nanocapsule (MLNC) functionalized with captopril and nanoencapsulating furosemide within the core was developed as a liquid formulation for oral administration. The nanocapsules had mean particle size below 200 nm, showing unimodal and narrow size distributions with moderate di...

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Detalles Bibliográficos
Autores principales: Michalowski, Cecilia B., Arbo, Marcelo D., Altknecht, Louise, Anciuti, Andréia N., Abreu, Angélica S. G., Alencar, Luciana M. R., Pohlmann, Adriana R., Garcia, Solange C., Guterres, Sílvia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022513/
https://www.ncbi.nlm.nih.gov/pubmed/31963659
http://dx.doi.org/10.3390/pharmaceutics12010080