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Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson’s Disease through Activating Mitophagy

Parkinson’s disease (PD) is a neurodegenerative disease, which is associated with mitochondrial dysfunction and abnormal protein accumulation. No treatment can stop or slow PD. Autophagy inhibits neuronal death by removing damaged mitochondria and abnormal protein aggregations. Celastrol is a triter...

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Detalles Bibliográficos
Autores principales: Lin, Ming-Wei, Lin, Chi Chien, Chen, Yi-Hung, Yang, Han-Bin, Hung, Shih-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022523/
https://www.ncbi.nlm.nih.gov/pubmed/31906147
http://dx.doi.org/10.3390/antiox9010037