Spironolactone-Loaded LeciPlexes as Potential Topical Delivery Systems for Female Acne: In Vitro Appraisal and Ex Vivo Skin Permeability Studies

Spironolactone (SP), an aldosterone antagonist with anti-androgen properties, has shown promising results in the treatment of female acne. However, its systemic side effects limit its clinical benefits. This study aimed to prepare and evaluate LeciPlexes for SP topical delivery. LeciPlexes were prep...

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Detalles Bibliográficos
Autores principales: Salama, Ayman, Badran, Mohamed, Elmowafy, Mohammed, Soliman, Ghareb M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022583/
https://www.ncbi.nlm.nih.gov/pubmed/31881783
http://dx.doi.org/10.3390/pharmaceutics12010025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022583/
https://www.ncbi.nlm.nih.gov/pubmed/31881783
http://dx.doi.org/10.3390/pharmaceutics12010025

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