Stability and Compatibility Studies of Levothyroxine Sodium in Solid Binary Systems—Instrumental Screening

The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with a narrow therapeutic index, the interactions of LTSS with excipients can lead to a drastic diminution of therapeu...

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Detalles Bibliográficos
Autores principales: Ledeți, Ionuț, Romanescu, Mirabela, Cîrcioban, Denisa, Ledeți, Adriana, Vlase, Gabriela, Vlase, Titus, Suciu, Oana, Murariu, Marius, Olariu, Sorin, Matusz, Petru, Buda, Valentina, Piciu, Doina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://www.ncbi.nlm.nih.gov/pubmed/31936742
http://dx.doi.org/10.3390/pharmaceutics12010058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://www.ncbi.nlm.nih.gov/pubmed/31936742
http://dx.doi.org/10.3390/pharmaceutics12010058

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