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Insight into the Formation of Glimepiride Nanocrystals by Wet Media Milling
Nanocrystal formation for the dissolution enhancement of glimepiride was attempted by wet media milling. Different stabilizers were tested and the obtained nanosuspensions were solidified by spray drying in presence of mannitol, and characterized regarding their redispersibility by dynamic light sca...
Autores principales: | Medarević, Djordje, Ibrić, Svetlana, Vardaka, Elisavet, Mitrić, Miodrag, Nikolakakis, Ioannis, Kachrimanis, Kyriakos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022670/ https://www.ncbi.nlm.nih.gov/pubmed/31936609 http://dx.doi.org/10.3390/pharmaceutics12010053 |
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