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Montelukast Nanocrystals for Transdermal Delivery with Improved Chemical Stability

A novel nanocrystal system of montelukast (MTK) was designed to improve the transdermal delivery, while ensuring chemical stability of the labile compound. MTK nanocrystal suspension was fabricated using acid-base neutralization and ultra-sonication technique and was characterized as follows: approx...

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Detalles Bibliográficos
Autores principales: Im, Sung Hyun, Jung, Hoe Taek, Ho, Myoung Jin, Lee, Jeong Eun, Kim, Hyung Tae, Kim, Dong Yoon, Lee, Hyo Chun, Choi, Yong Seok, Kang, Myung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022715/
https://www.ncbi.nlm.nih.gov/pubmed/31877986
http://dx.doi.org/10.3390/pharmaceutics12010018