Melatonin Prevents Transforming Growth Factor-β1-Stimulated Transdifferentiation of Renal Interstitial Fibroblasts to Myofibroblasts by Suppressing Reactive Oxygen Species-Dependent Mechanisms

Accumulating evidence suggests that the pineal hormone melatonin displays protective effects against renal fibrosis, but the mechanisms remain poorly understood. Here, we investigate the effect of the pineal hormone on transdifferentiation of renal fibroblasts to myofibroblasts invoked by transformi...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Yeon, Park, Jae-Hyung, Jeon, Eon Ju, Leem, Jaechan, Park, Kwan-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022732/
https://www.ncbi.nlm.nih.gov/pubmed/31906396
http://dx.doi.org/10.3390/antiox9010039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022732/
https://www.ncbi.nlm.nih.gov/pubmed/31906396
http://dx.doi.org/10.3390/antiox9010039

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