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Dual pH- and GSH-Responsive Degradable PEGylated Graphene Quantum Dot-Based Nanoparticles for Enhanced HER2-Positive Breast Cancer Therapy

Dual stimuli-responsive degradable carbon-based nanoparticles (DS-CNPs) conjugated with Herceptin (HER) and polyethylene glycol (PEG) have been designed for the treatment of HER2-positive breast cancer. Each component has been linked through disulfide linkages that are sensitive to glutathione in a...

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Detalles Bibliográficos
Autores principales: Ko, Na Re, Van, Se Young, Hong, Sung Hwa, Kim, Seog-Young, Kim, Miran, Lee, Jae Seo, Lee, Sang Ju, Lee, Yong-kyu, Kwon, Il Keun, Oh, Seung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022825/
https://www.ncbi.nlm.nih.gov/pubmed/31906509
http://dx.doi.org/10.3390/nano10010091