Mercury and Alzheimer’s Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization

Brains and blood of Alzheimer’s disease (AD) patients have shown elevated mercury concentrations, but potential involvement of mercury exposure in AD pathogenesis has not been studied at the molecular level. The pathological hallmark of AD brains is deposition of amyloid plaques, consisting mainly o...

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Detalles Bibliográficos
Autores principales: Wallin, Cecilia, Friedemann, Merlin, Sholts, Sabrina B., Noormägi, Andra, Svantesson, Teodor, Jarvet, Jüri, Roos, Per M., Palumaa, Peep, Gräslund, Astrid, Wärmländer, Sebastian K. T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022868/
https://www.ncbi.nlm.nih.gov/pubmed/31892131
http://dx.doi.org/10.3390/biom10010044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022868/
https://www.ncbi.nlm.nih.gov/pubmed/31892131
http://dx.doi.org/10.3390/biom10010044

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