A Novel Testing Approach for Oxidative Degradation Dependent Incompatibility of Amine Moiety Containing Drugs with PEGs in Solid-State

Reactive impurities originating from excipients can cause drug stability issues, even at trace amounts. When produced during final dosage form storage, they are especially hard to control, and often, factors inducing their formation remain unidentified. Oxidative degradation dependent formation of f...

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Detalles Bibliográficos
Autores principales: Robnik, Blaž, Naumoska, Katerina, Časar, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022946/
https://www.ncbi.nlm.nih.gov/pubmed/31906507
http://dx.doi.org/10.3390/pharmaceutics12010037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022946/
https://www.ncbi.nlm.nih.gov/pubmed/31906507
http://dx.doi.org/10.3390/pharmaceutics12010037

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