High Levels of Glutaminase II Pathway Enzymes in Normal and Cancerous Prostate Suggest a Role in ‘Glutamine Addiction’

Many tumors readily convert l-glutamine to α-ketoglutarate. This conversion is almost invariably described as involving deamidation of l-glutamine to l-glutamate followed by a transaminase (or dehydrogenase) reaction. However, mammalian tissues possess another pathway for conversion of l-glutamine t...

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Detalles Bibliográficos
Autores principales: Dorai, Thambi, Dorai, Bhuvaneswari, Pinto, John T., Grasso, Michael, Cooper, Arthur J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022959/
https://www.ncbi.nlm.nih.gov/pubmed/31861280
http://dx.doi.org/10.3390/biom10010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022959/
https://www.ncbi.nlm.nih.gov/pubmed/31861280
http://dx.doi.org/10.3390/biom10010002

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