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Intrinsic Disorder-Based Design of Stable Globular Proteins

Directed stabilization of globular proteins via substitution of a minimal number of amino acid residues is one of the most complicated experimental tasks. This work summarizes our research on the effect of amino acid substitutions on the protein stability utilizing the outputs of the analysis of int...

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Detalles Bibliográficos
Autores principales: Nagibina, Galina S., Glukhova, Ksenia A., Uversky, Vladimir N., Melnik, Tatiana N., Melnik, Bogdan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022990/
https://www.ncbi.nlm.nih.gov/pubmed/31906016
http://dx.doi.org/10.3390/biom10010064