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Neuroprotective γ-Pyrones from Fusarium Solani JS-0169: Cell-Based Identification of Active Compounds and an Informatics Approach to Predict the Mechanism of Action

Glutamate toxicity has been implicated in neuronal cell death in both acute CNS injury and in chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, Fusarium solani JS-0169 isolated from the leaves of Morus alba...

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Detalles Bibliográficos
Autores principales: Choi, Hyun Gyu, Song, Ji Hoon, Park, Musun, Kim, Soonok, Kim, Chang-Eop, Kang, Ki Sung, Shim, Sang Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023011/
https://www.ncbi.nlm.nih.gov/pubmed/31935895
http://dx.doi.org/10.3390/biom10010091