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Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation

Antimicrobial treatment in critically ill patients remains challenging. The aim of this study was to develop a population pharmacokinetic model for linezolid in critically ill patients and to evaluate the adequacy of current dosing recommendation (600 mg/12 h). Forty inpatients were included, 23 of...

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Detalles Bibliográficos
Autores principales: Soraluce, Amaia, Barrasa, Helena, Asín-Prieto, Eduardo, Sánchez-Izquierdo, Jose Ángel, Maynar, Javier, Isla, Arantxazu, Rodríguez-Gascón, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023070/
https://www.ncbi.nlm.nih.gov/pubmed/31936614
http://dx.doi.org/10.3390/pharmaceutics12010054