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Gastrointestinal Tracking and Gastric Emptying of Coated Capsules in Rats with or without Sedation Using CT imaging

Following oral administration, gastric emptying is often a rate-limiting step in the absorption of drugs and is dependent on both physiological and pharmaceutical factors. To guide translation into humans, small animal imaging during pre-clinical studies has been increasingly used to localise the ga...

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Detalles Bibliográficos
Autores principales: Gómez-Lado, Noemí, Seoane-Viaño, Iria, Matiz, Silvia, Madla, Christine M., Yadav, Vipul, Aguiar, Pablo, Basit, Abdul W., Goyanes, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023106/
https://www.ncbi.nlm.nih.gov/pubmed/31963818
http://dx.doi.org/10.3390/pharmaceutics12010081